CASE STUDIES
Therapies with PATHELEN® HYBRID
In recent years, PATHELEN® HYBRID therapy has been tested on patients in various hospitals and continuously developed. Various wound infections were successfully treated until the patient had completely healed and recovered.
Name:
B.G.O., female, 67 y.o.
Diagnosis:
Infected wound of abdominal wall
Microflora:
Staphylococcus aureus
White blood cells (WBCs): 10,2×109/l
Banded neutrophils – 8%.
The patient was acepted with complaints on the pain and wounds on the anterior abdominal wall, the temperature of 36,7 C.Ps – 98/min. AP – 130/80 mm Hg.
The disease has started 4 days ago.
Name:
N.O.O., male, 62 y.o.
Diagnosis:
Type 2 diabetes mellitus, diabetic foot syndrome neuroischemic form, abscess of the left tibia, abscess of the left leg.
Microflora:
Staphylococcus aureus
White blood cells (WBCs): 13,5×109/l
Banded neutrophils – 28%.
The patient was accepted with complaints on pain and wounds on the anterior abdominal wall, the temperature 38.2C.Ps – 100/min. AP – 120/80 mm Hg.
The disease has began 6 days ago.
Name:
M.I., female, 20 y.o.
Diagnosis:
Acute posterior anorectal abscess
Case relevant history:
Neurocirculatory dystonia, mixed type.
Epilepsy
Microflora:
Escherichia coli
White blood cells (WBCs): 10,0×109/l
Banded neutrophils – 8%.
The patient was admitted with complaints of pain in his left leg, redness and itching on the internal surface of the left tibia and femur.
Fever up to 39.5 °C, hemoglobin: Hb-80 g/l, and frequency of puls – 110/min showed that the patient had Systemic Inflammatory Response Syndrome (SIRS). Based on existence of purulent inflammation and SIRS, the Patient was diagnosed – Sepsis.
Name:
E.A.M., female, 43 y.o.
Diagnosis:
Carbuncle anterior abdominal wall
Microflora:
Staphylococcus saprophyticus
Staphylococcus aureus
White blood cells (WBCs): 13,3×109/l
Banded neutrophils – 7%.
Complaints on the pain and swelling near the anus. Fever up to 37.9 °C. Heart rate – 88 bpm. AP – 120/70 mm Hg. The disease began 2 days ago.
Name:
L.V.I., male, 38 y.o.
Diagnosis:
Acute ischiorectal abscess. Sepsis
Case relevant history:
Myocardiosclerosis. Atrial flutter-fibrillation. Tachysystole. Heart failure I-II A.
Alimentary-constitutional obesity (weight- 170 kg; body mass index- 46)
Microflora:
Escherichia coli
Enterococcus faecalis
White blood cells (WBCs): 21,6×109/l
Banded neutrophils – 10%.
Fever up to 39.5 °C, and heart rate – 98 bpm showed that the patient had Systemic Inflammatory Response Syndrome (SIRS). Based on existence of purulent inflammation and SIRS, the Patient was diagnosed – Sepsis
Name:
M.A., female, 78 y.o.
Diagnosis:
Necrotizing fasciitis of the left shin Thrombophlebitis of the left tibia. Chronic venous insufficiency 6c.
Microflora:
Staphylococcus aureus
Pseudomonas aeruginosa
White blood cells (WBCs): 14,03×109/l
Banded neutrophils – 19%.
The patient was hospitalized with complaints of pain in the left leg, the temperature of 37.8C.
Ps – 100/min. AP – 140/80 mm Hg.
Name:
Z.V. male, 68 y.o.
Diagnosis:
Type 2 diabetes mellitus, diabetic foot syndrome neuroischemic form; wound infection of the left foot after amputation of fingers
Case relevant history:
Ischemic heart disease
Hypertensive heart disease
Heart failure
Atrial fibrillation is a permanent form
Microflora:
Staphylococcus aureus
Staphylococcus epidermidis
Enterococcus faecium
White blood cells (WBCs): 8,0×109/l
Banded neutrophils – 8%
On the lateral surface of the left foot was observed infected wound sized 9 х 3 cm
Name:
C.M., male, 44 y.o.
Diagnosis:
Acute anterior anorectal extrasphincteric abscess
Case relevant history:
Ischemic heart diseas
Atherosclerotic cardiosclerosis.
Heart failure I
Supraventricular extrasystoles
Microflora:
Escherichia coli
Acinetobacter baumannii
Enterococcus faecium
White blood cells (WBCs): 6,4×109/l
Banded neutrophils – 9%.
Skin hyperemia without precise borders is visualized in 13 hours on conditional dial in the perianal region, in 4-5 cm from the anus – infiltrate 6×11 cm, the infiltrate is hot to the touch, painful, with soft area in its center.
Name:
M.T., male, 20 y.o.
Diagnosis:
Acute pilonidal abscess (sacrococcygeal region).
Microflora:
Escherichia coli (E. coli)
White blood cells (WBCs): 12,5×109/l
Banded neutrophils – 11%.
Complaints on the pain and swelling in the cleft on the top of buttocks.
Name:
l.M., female, 68 y.o.
Diagnosis:
Necrotic abscess suprapubic area and perineum
Case relevant history:
Type 2 diabetes mellitus
Chronic iron deficiency anemia
Microflora:
Proteus mirabilis
Staphylococcus epidermidis
Klebsiella orytoca
Citrobacter freundii
Klebsiella pneumoniae
Staphylococcus epidermidis
White blood cells (WBCs): 18,2×109/l
Banded neutrophils – 29%.
Fever up to 38.5 °C, leukocytosis – 18,2×109/l with banded neutrophils – 29%, hemoglobin: Hb-72g/l, and frequency of pulse – 120/min showed that the patient had Systemic Inflammatory Response Syndrome (SIRS). Based on existence of purulent inflammation and SIRS, the Patient was diagnosed – Sepsis
Name:
B.A., male, 61 y.o.
Diagnosis:
Diabetes mellitus type 2. Diabetic foot syndrome neuroischemic form, foot abscess, osteomyelitis of the foot bones. Sepsis
Case relevant history:
Chronic iron deficiency anemia caused by foot phlegmon
Microflora:
Enterococcus faecalis (E. faecalis)
Staphylococcus saprophyticus (S. Saprophyticuі)
Staphylococcus epidermidis (S. epidermidis)
White blood cells (WBCs): 20,3×109/l
Banded neutrophils – 17%.
Complaints on the pain in the foot, pus from the wound, increasing fever up to 39.5 °C
Name:
A.N., male, 59 y.o.
Diagnosis:
Chronic infected wound to the left lower leg
Case relevant history:
Diabetes mellitus type 2. Chronic venous disorders.
Microflora:
Staphylococcus saprophyticus (S. Saprophyticuі)
Staphylococcus epidermidis (S. epidermidis)
White blood cells (WBCs): 8,0×109/l
Banded neutrophils – 6%.
Complaints on the wound on the front surface of the lower part of the left leg which patient has had for the last 5 months. The patient noted constant pain in the wound.
Name:
- V., male, 48 y.o.
Diagnosis:
Diabetes mellitus type 2, diabetic foot syndrome neuropathic form, and trophic ulcers of both feet. Wagner 2 right foot. Wagner 3 left foot.
Microflora:
Staphylococcus aureus (S. aureus) MRSA
Enterobacter cloacae (E. cloacae)
Staphylococcus epidermidis (S. epidermidis)
White blood cells (WBCs): 4,8×109/l
Banded neutrophils – 5%.
The patient was accepted into the hospital with complaints on the wound on the left foot, the patient have noted the wound 6 months ago.
Name:
I.V., male, 50 y.o.
Diagnosis:
Acute posterior ischio- and retrorectal extrasphincteric abscess. Sepsis
Case relevant history:
Diabetes mellitus type 2. Obesity. Hypertensive heart disease, stage ІІ. Ischemic heart disease.
Microflora:
Acinetobacter baumannii (A. baumannii)
Escherichia coli (E. coli)
White blood cells (WBCs): 12.0×109/l
Banded neutrophils – 9%.
Fever up to 39.5 °C, leukocytosis – 12.0×109/l, heart rate 120 bpm and breathing frequency 20/min showed that the patient had Systemic Inflammatory Response Syndrome. Based on existence of purulent inflammation and SIRS, the Patient was diagnosed – Sepsis.
Name:
L.B., female, 63 y.o.
Diagnosis:
Acute right sided ischiorectal abscess
Case relevant history:
Diabetes mellitus type 2, Obesity (body mass index – 37 kg/m2), Arterial hypertension, Ischemic heart disease, Atherosclerotic cardiosclerosis, Metabolic cardiomyopathy
Microflora:
Enterococcus faecalis
Staphylococcus epidermidis
White blood cells (WBCs): 18.2×109/l
Banded neutrophils – 19%.
Fever up to 38.5 °C, leukocytosis – 18.2×109/l with banded neutrophils – 19%, heart rate – 110 bpm showed that the patient had Systemic Inflammatory Response Syndrome. Based on existence of purulent inflammation and SIRS, the Patient was diagnosed – Sepsis.
Name:
L.S., female, 40 y.o.
Diagnosis:
Acute posterior retro-rectal trans-sphincteric abscess
Case relevant history:
Arterial hypertension
Microflora:
Escherichia coli (E. coli)
Enterococcus faecium (E. faecium)
White blood cells (WBCs): 9.0×109/l
Banded neutrophils – 12%.
Fever up to 38.2 °C, leukocytosis – 9.0×109/l with banded neutrophils – 12% showed that the patient had Systemic Inflammatory Response Syndrome.
